Affexor XR (Venlafaxine) 150 mg Tablet is a serotonin-norepinephrine reuptake inhibitor used to treat major depressive disorder, anxiety, and panic attacks. It is also considered a second-line option for the management of obsessive-compulsive disorder (OCD).

How does Affexor XR (Venlafaxine) 150 mg Tablet work?

The exact mechanism of action of Venlafaxine is unknown, but it appears to be related to the potentiation of neurotransmitter activity in the central nervous system. Venlafaxine and its active metabolite, O-desmethylvenlafaxine, inhibits the reuptake of both serotonin and norepinephrine metabolites and has weak inhibitory effects on the reuptake of dopamine. It is not active at histaminergic, muscarinic, or alpha(1)-adrenergic receptors, unlike serotonin selective reuptake inhibitors (SSRIs).

How to take Affexor XR (Venlafaxine) 150 mg

This medicine should be taken together with food or immediately after a meal. Try to take it at the same time each day.

Affexor XR (Venlafaxine) 150 mg Tablet must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed. Stopping it suddenly could worsen your condition.

Take Affexor XR (Venlafaxine) 150 mg Tablet precisely as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

Missed Dose

If you miss a dose, skip the missed dose and return to your usual dosing schedule. If you often forget to take your medicine, let your doctor and pharmacist know. Do not double a dose under any circumstances.

Overdose of Affexor XR (Venlafaxine)

Signs of overdose may include the following:

- Tachycardia;

- Changes in the level of consciousness;

- Mydriasis;

- Convulsion;

- Vomiting;

- ECG changes (e.g., prolonged QT interval, QRS prolongation, bundle branch block);

- Ventricular tachycardia;

- Bradycardia;

- Hypotension;

- Vertigo;

- Rhabdomyolysis and death.

Seek medical help immediately.

Affexor XR (Venlafaxine) may have the following side effects:

- Withdrawal symptoms (e.g., dizziness, sensory and sleep disturbances, agitation, nausea, vomiting, headache);

- Anxiety;

- Insomnia;

- Nervousness;

- Central nervous system depression

- Dyslipidemia;

- Bone fracture;

- Hypertension;

- Sexual dysfunction;

- Weight loss and anorectic effect;

- Mild pupillary dilation;

- Suicidal thoughts and behaviour.

Storage Conditions

Store it between 20-25°C. Protect it from light and moisture.

Store it in a cool, dry place away from the reach of children.

Do not use Affexor XR (Venlafaxine) that is expired or out of date.